4-Pyridinecarboxylic acid, 2-chloro-5-nitro-

4-Pyridinecarboxylic acid, 2-chloro-5-nitro- - Names and Identifiers

Name	2-chloro-5-nitro-pyridine-4-carboxylic acid
Synonyms	LogP 2-Chloro-5-nitro isonicotinic acid 2-chloro-5-nitropyridine-4-carboxylic acid 2-chloro-5-nitropyridine-4-carbo×ylic acid 2-chloro-5-nitro-4-Pyridinecarboxylic acid 2-chloro-5-nitro-pyridine-4-carboxylic acid 4-Pyridinecarboxylic acid, 2-chloro-5-nitro-
CAS	907545-47-5
InChI	InChI=1/C6H3ClN2O4/c7-5-1-3(6(10)11)4(2-8-5)9(12)13/h1-2H,(H,10,11)

4-Pyridinecarboxylic acid, 2-chloro-5-nitro- - Physico-chemical Properties

Molecular Formula	C6H3ClN2O4
Molar Mass	202.55
Density	1.702±0.06 g/cm3(Predicted)
Boling Point	480.2±45.0 °C(Predicted)
Flash Point	244.188°C
Vapor Presure	0mmHg at 25°C
pKa	1.08±0.25(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.637

4-Pyridinecarboxylic acid, 2-chloro-5-nitro- - Introduction

Acid (acid) is an organic compound. Its molecular formula is C6H3ClN2O4, the structure contains a ring of pyridine, and in the 4 position on the pyridine ring is attached to a carboxyl group, while in the 2 and 5 position attached to a chlorine and a nitro group. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is light yellow to yellow crystal powder.
-Solubility: Its solubility in water is low, but it is soluble in most organic solvents such as alcohols, ethers and ketones.
-Thermal stability: Decomposition may occur at high temperatures.
-Chemical properties: It is an acidic organic compound that can participate in chemical reactions such as esterification and substitution reactions.

Use:
-acid is commonly used as a starting material in organic synthesis and can be used to synthesize other compounds, such as oxamide pesticides, oxamine phosphorus, etc.
-It can also be used in the research and preparation of organic light-emitting diodes (OLED) and other devices.

Method:
A common preparation method is to synthesize from pyridine as a starting material through chlorination and nitration reactions. The specific steps are more complex and require multi-step reactions, including chlorination, nitration, carboxylation, etc., which are operated in a chemical laboratory.

Safety Information:
-the acid should be stored in a cool, dry place, away from direct sunlight.
-Wear personal protective equipment such as goggles and gloves during operation.
-It may cause irritation and damage to the eyes, skin and respiratory tract, so contact should be avoided during operation.
-In case of inhalation, contact or accidental ingestion, please seek medical attention.

Last Update：2024-04-10 22:29:15